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Korean J. Vet. Serv. 2016; 39(2): 117-124

Published online June 30, 2016

https://doi.org/10.7853/kjvs.2016.39.2.117

© The Korean Socitety of Veterinary Service

Ortho-phenylphenol을 주성분으로 하는 훈증소독제의 돼지열병바이러스와 돼지생식기호흡기증후군바이러스에 대한 살바이러스 효과

차춘남;박은기;정지윤;유창열;김석;이후장;

경상대학교 공과대학 공학연구원;고신대학교 의과대학;공주대학교 특수동물학과;경남도립남해대학 스마트융합정보과;경상대학교 수의과대학 동물의학연구소;경상대학교 수의과대학 동물의학연구소;

Received: May 18, 2016; Revised: June 24, 2016; Accepted: June 26, 2016

Virucidal efficacy of a fumigant containing orth-phenylphenol against classical swine fever virus and porcine reproductive and respiratory syndrome virus

Cha, Chun-Nam;Park, Eun-Kee;Jung, Ji-Youn;Yoo, Chang-Yeul;Kim, Suk;Lee, Hu-Jang;

Department of Industrial Systems Engineering, Engineering Research Institute, Gyeongsang National University;Department of Medical Humanities and Social Medicine, College of Medicine, Kosin University;Department of Companion and Laboratory Animal Science, Kongju National University;Department of Smart Information Convergence, Gyeongnam Provincial Namhae College;Institute of Animal Medicine, College of Veterinary Medicine, Gyeongsang National University;Institute of Animal Medicine, College of Veterinary Medicine, Gyeongsang National University;

Correspondence to : 경상대학교 수의과대학 동물의학연구소(Institute of Animal Medicine, College of Veterinary Medicine, Gyeongsang National University)

Received: May 18, 2016; Revised: June 24, 2016; Accepted: June 26, 2016

Abstract

In this study, the virucidal efficacy of a fumigant containing 20% ortho-phenylphenol against classical swine fever virus (CSFV) and porcine reproductive and respiratory syndrome virus (PRRSV) was examined. After each carrier deposited with CSFV and PRRSV suspensions was exposed to the fumigant in a $25-m^3$ test room for 15 h, all carriers were neutralized and diluted, and each diluted suspension was inoculated into each proper cell line. After incubation, CSFV and PRRSV viability in each cell line was examined and 50% tissue culture infectious dose $(TCID_{50})/mL$ was calculated. In the results, the concentration of viable virus in all of pathogen control-carriers was more than $2{ imes}10^5TCID_{50}/mL$, and there were no cytotoxicity in all of toxicity control-carriers. In addition, the fumigant inactivated ${geq}4.8{log}_{10}(TCID_{50}/mL)$ of both CSFV and PRRSV. These findings will be useful for preventing the spread of CSFV and PRRSV infection.

Keywords Fumigation,Ortho-phenylphenol,Classical swine fever virus,Porcine reproductive and Respiratory syndrome virus,Virucidal efficacy,

Article

Research Article

Korean J. Vet. Serv. 2016; 39(2): 117-124

Published online June 30, 2016 https://doi.org/10.7853/kjvs.2016.39.2.117

Copyright © The Korean Socitety of Veterinary Service.

Ortho-phenylphenol을 주성분으로 하는 훈증소독제의 돼지열병바이러스와 돼지생식기호흡기증후군바이러스에 대한 살바이러스 효과

차춘남;박은기;정지윤;유창열;김석;이후장;

경상대학교 공과대학 공학연구원;고신대학교 의과대학;공주대학교 특수동물학과;경남도립남해대학 스마트융합정보과;경상대학교 수의과대학 동물의학연구소;경상대학교 수의과대학 동물의학연구소;

Received: May 18, 2016; Revised: June 24, 2016; Accepted: June 26, 2016

Virucidal efficacy of a fumigant containing orth-phenylphenol against classical swine fever virus and porcine reproductive and respiratory syndrome virus

Cha, Chun-Nam;Park, Eun-Kee;Jung, Ji-Youn;Yoo, Chang-Yeul;Kim, Suk;Lee, Hu-Jang;

Department of Industrial Systems Engineering, Engineering Research Institute, Gyeongsang National University;Department of Medical Humanities and Social Medicine, College of Medicine, Kosin University;Department of Companion and Laboratory Animal Science, Kongju National University;Department of Smart Information Convergence, Gyeongnam Provincial Namhae College;Institute of Animal Medicine, College of Veterinary Medicine, Gyeongsang National University;Institute of Animal Medicine, College of Veterinary Medicine, Gyeongsang National University;

Correspondence to:경상대학교 수의과대학 동물의학연구소(Institute of Animal Medicine, College of Veterinary Medicine, Gyeongsang National University)

Received: May 18, 2016; Revised: June 24, 2016; Accepted: June 26, 2016

Abstract

In this study, the virucidal efficacy of a fumigant containing 20% ortho-phenylphenol against classical swine fever virus (CSFV) and porcine reproductive and respiratory syndrome virus (PRRSV) was examined. After each carrier deposited with CSFV and PRRSV suspensions was exposed to the fumigant in a $25-m^3$ test room for 15 h, all carriers were neutralized and diluted, and each diluted suspension was inoculated into each proper cell line. After incubation, CSFV and PRRSV viability in each cell line was examined and 50% tissue culture infectious dose $(TCID_{50})/mL$ was calculated. In the results, the concentration of viable virus in all of pathogen control-carriers was more than $2{ imes}10^5TCID_{50}/mL$, and there were no cytotoxicity in all of toxicity control-carriers. In addition, the fumigant inactivated ${geq}4.8{log}_{10}(TCID_{50}/mL)$ of both CSFV and PRRSV. These findings will be useful for preventing the spread of CSFV and PRRSV infection.

Keywords: Fumigation,Ortho-phenylphenol,Classical swine fever virus,Porcine reproductive and Respiratory syndrome virus,Virucidal efficacy,

KJVS
Dec 30, 2024 Vol.47 No.4, pp. 193~317

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Korean Journal of
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