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Korean J. Vet. Serv. 2024; 47(3): 157-164
Published online September 30, 2024
https://doi.org/10.7853/kjvs.2024.47.3.157
© The Korean Socitety of Veterinary Service
조혜진*
질병관리청 국립보건연구원 신종바이러스매개체연구과
Correspondence to : Hyejean Cho
E-mail: hcho21@snu.ac.kr
https://orcid.org/0009-0000-9461-2013
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0). which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
The aim of this study was to assess and compare the toxicity and safety of two types of propolis (liquid and powder) in beagle dogs. Blood counts, serum biochemistry, and electrolyte tests were conducted to evaluate acute oral toxicity. Propolis was administered at a 5% concentration and 40 g dosage, and the beagles were monitored for 8 weeks. Three beagles served as controls, while four beagles each were assigned to the liquid and powder groups. No significant clinical signs or changes in feed intake, water consumption, body condition, or hematological/biochemical parameters were observed. The results indicate that oral administration of both liquid and powder propolis does not induce toxicological effects in beagle.
Keywords Propolis, Beagle, Hematology, Serum biochemistry, Safety
Korean J. Vet. Serv. 2024; 47(3): 157-164
Published online September 30, 2024 https://doi.org/10.7853/kjvs.2024.47.3.157
Copyright © The Korean Socitety of Veterinary Service.
조혜진*
질병관리청 국립보건연구원 신종바이러스매개체연구과
Division of Emerging Virus & Vector Research, Korea National Institute of Health, Korea Disease Control and Prevention Agency, Cheongju 28159, Korea
Correspondence to:Hyejean Cho
E-mail: hcho21@snu.ac.kr
https://orcid.org/0009-0000-9461-2013
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0). which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
The aim of this study was to assess and compare the toxicity and safety of two types of propolis (liquid and powder) in beagle dogs. Blood counts, serum biochemistry, and electrolyte tests were conducted to evaluate acute oral toxicity. Propolis was administered at a 5% concentration and 40 g dosage, and the beagles were monitored for 8 weeks. Three beagles served as controls, while four beagles each were assigned to the liquid and powder groups. No significant clinical signs or changes in feed intake, water consumption, body condition, or hematological/biochemical parameters were observed. The results indicate that oral administration of both liquid and powder propolis does not induce toxicological effects in beagle.
Keywords: Propolis, Beagle, Hematology, Serum biochemistry, Safety
Kang, Ikjae;
Korean J. Vet. Serv. 2019; 42(4): 305-311 https://doi.org/10.7853/kjvs.2019.42.4.305Hyejean Cho
Korean J. Vet. Serv. 2024; 47(3): 165-172 https://doi.org/10.7853/kjvs.2024.47.3.165Yi, Seung-Won;Kim, Eunju;Oh, Sang-Ik;Ha, Ji-Hong;Lee, Bugeun;Yoo, Jae Gyu;Do, Yoon Jung;
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